• br A few years ago my group published

  2019-04-17

  

  A few years ago, my group published an article entitled uhuru. is the Swahili word for “freedom”. The idea was to highlight the plight of patients with end-stage kidney disease (ESKD) and the challenges and frustrations of their nephrologists in sub-Saharan Africa amidst health-care authorities th

• Another recent study also concluded that presence

  2019-04-17

  

  Another recent study also concluded that presence of EMD at diagnosis, rather than any treatment modalities ever used, was the only significant predictor of extramedullary recurrence. This finding suggests that the development of EMD, even during treatment, may possibly reflect different tumor biolo

• mg115 One significant problem associated with chronic condit

  2019-04-17

  

  One significant problem associated with chronic conditions is the lack of treatment persistence and compliance. It has been demonstrated that around 50% of patients suffering from such conditions discontinue their therapy early [10]. In the case of BC, older women are known to be at a higher risk of

• Phosphorus is essential for organic activity such as cellula

  2019-04-17

  

  Phosphorus is essential for organic activity such as cellular signal transduction, membrane transport, mineral metabolism, and dpp-4 inhibitor exchange [1]. Bone and teeth store 80% of the total body phosphorus. Intracellular phosphorus consists of the form of organic compounds such as adenosine tr

• Our findings show that primary prevention ICD

  2019-04-16

  

  Our findings show that primary prevention ICD recipients experienced an impaired QOL on vitality subscales, which were included in the physical health domain, compared to secondary prevention ICD recipients. Similarly, Berg et al. also found that ICD patients with a primary prevention indication had

• br Conformational control inhibition Conformational escape r

  2019-04-16

  

  Conformational control inhibition Conformational escape resistance is a phenomenon where point mutations (such as T315I) drive the Abl kinase toward the active type I state. “Switch-control inhibitors” bind in a non-ATP-competitive fashion to residues (E282, R386) the Abl protein uses to switch b

• Despite taking hydroxyurea for months his leukocytosis

  2019-04-16

  

  Despite taking hydroxyurea for 6 months, his leukocytosis, splenomegaly, and constitutional symptoms were poorly controlled and his performance status and overall function had declined even further. There was little clinical benefit to gain by increasing the hydroxyurea dose further especially in th

• Amiodarone has been used in Japan for more than years

  2019-04-16

  

  Amiodarone has been used in Japan for more than 5 years now since its approval in July 2007, and intravenous amiodarone has been widely used for life-threatening ventricular tachycardia in the setting of critical care medicine. However, only few reports have been published in the international liter

• itk inhibitor Herweg et al evaluated the

  2019-04-16

  

  Herweg et al. [9] evaluated the benefit of CRT in 10 consecutive patients with NYHA class IV HF who were dependent on inotropic support. Their patients had received inotropic support for 146±258 days, and all patients were alive at the mean follow-up of 1088±284 days after CRT. They also reported an

• btk inhibitor Roux en Y gastric bypass

  2019-04-16

  

  Roux-en-Y gastric bypass surgery is a common cause of malabsorption associated with hyperoxaluria in obese patients and those with malignancies. Postoperatively, patients may have steatorrhea, weight loss, and diarrhea, resulting in malabsorption syndrome, which would increase excessive intraluminal

• A first step is reconsideration

  2019-04-16

  

  A first step is reconsideration of the term family planning. This debate is not simply a question of semantics—language is a powerful ideological and political statement. Discourse creates a representation of the world; it perpetuates a cultural and social reality. In this sense, language is action

• Sin embargo esta intervenci n del

  2019-04-16

  

  Sin embargo, esta intervención del Estado en asuntos culturales es propia de una etapa anterior nrf2 keap1 los incontenibles procesos de modernización y democratización de la sociedad latinoamericana. De acuerdo con José Luis Romero, desde 1880, las nuevas relaciones entre los países industrializado

• get the job To clarify the mechanisms of

  2019-04-15

  

  To clarify the mechanisms of nerve regeneration by electrical stimulation, we investigated differentiation and cellular damage of drug-hypersensitive PC12m3 mutant get the job caused by electrical stimulation. We obtained PC12m3 cells from a variant cell line of PC12 cells that spontaneously showed

• Introduction This document does not address the

  2019-04-15

  

  Introduction This document does not address the indications of genetic testing in patients affected by inherited arrhythmias and their family members. Diagnostic, prognostic, and therapeutic implications of the results of genetic testing also are not included in this document because this topic has

• Introduction The assessment of hormonal receptor

  2019-04-15

  

  Introduction The assessment of hormonal receptor (HR) and human epidermal growth factor receptor-2 (HER2) status by immunohistochemistry (IHC) groups breast cancer into three major subtypes: 1) luminal-like subtype (HR positive/HER2 negative); 2) HER2 subtype (HER2 positive and HR negative/positive

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