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br Rheumatic heart disease RHD
2019-06-19

Rheumatic heart disease (RHD) affects over 32 million people worldwide; the vast majority of patients are in low-income and middle-income countries. It is a leading cause of premature mortality in children and young adults living in endemic regions. Patients with RHD often present in an advanced s
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In the case reported by
2019-06-19

In the case reported by Goldstein et al. [2], a Riata ST lead (St. Jude Medical, Sylmar, CA, USA) was used. The authors did not mention whether the lead was a dual-coil system or not. If the lead was a single-coil system, the possibility of an HV short circuit between the RV coil conductor and the d
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br Discussion This patient presented with a rare
2019-06-19

Discussion This patient presented with a rare case of ameboma and underwent a right hemicolectomy procedure. However, the patient did not survive the surgical intervention and post-operative period due to severe sepsis. The primary reason that treatment failed was due to delayed diagnosis and tre
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I am delighted to introduce
2019-06-18

I am delighted to introduce the inaugural issue of . It is very likely that you are reading this online, this being an online-only journal, although we have also printed this first issue in order to showcase the journal to readers of . What is certain is that, in accessing this article, and all the
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Stigma and discrimination experienced by sex workers injecti
2019-06-18

Stigma and discrimination experienced by sex workers, injection drug users, and men who have sex with men is tough to tackle. Responses need to be tailored to very different circumstances and require interventions on several levels: policy, societal, health system, and individual. There is no magic
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br Imagine providing care for
2019-06-18

Imagine providing care for 900 000 low birthweight (LBW; lighter than 2500 g) newborn babies each year in sub-Saharan Africa—all attributable to preventable and treatable malaria. Many of these LBW babies will be born in rural and impoverished settings where access to health care is poorest and t
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We agree that this method is
2019-06-18

We agree that this method is an appropriate way to assess whether Buruli ulcer is over-represented in children, but this issue was not central to our study. We also felt that the introduction of external data, the quality of which we cannot assess and which might not be relevant to areas where Burul
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br Point of care diagnostic tests POCTs can enable
2019-06-18

Point-of-care diagnostic tests (POCTs) can enable health-care workers to provide more rapid and effective care to people in low-resource settings. POCTs should ideally meet the WHO\'s ASSURED criteria—ie, being affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and
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EBV occasionally reactivates to switch its replication mode
2019-06-18

EBV occasionally reactivates to switch its replication mode from latent to lytic, producing a large number of infectious virions with the lysis of host cells [7]. Although reactivation is dangerous for the virus, its triggering factors have not yet been identified. EBV reactivation is associated not
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Despite the challenges since the
2019-06-18

Despite the challenges, since the Safe Motherhood Initiative was launched almost 30 years ago, international institutions such as the World Bank and WHO, and independent groups such as the Institute for Health Metrics and Evaluation, have developed, published, and continually refined estimates of ma
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br Conclusion br Conflict of interest br Introduction Classi
2019-06-18

Conclusion Conflict of interest Introduction Classically, cancer has been described as a disease involving uncontrolled cell growth. Now, however, it is apparent that cancer growth and metastasis are not solely dependent on the tumor TMN 355 themselves, but involve pathologies in the surro
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Pyoluteorin cost There are several limitations to the proced
2019-06-18

There are several limitations to the procedure described herein. The present GC was developed for engaging the coronary sinus via a right-sided approach. However, this GC was bent dorsally and had the shortest tip and most acute tip angle among the Attain™ family, which facilitated its placement int
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In contrast to adults PBL in children
2019-06-18

In CID 2745687 to adults, PBL in children is regarded as a clinical entity that is distinct from its adult counterpart. Like many other pediatric malignancies, PBL is considered a systemic disease in children. In small retrospective studies, PBL in children is characterized by rapid progression, a
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It has been speculated that the geographical
2019-06-18

It has been speculated that the geographical variation among radiotherapy prescription is a function of the respective healthcare systems within each region. If physicians receive greater reimbursement for multiple fractions compared to a single fraction, they will likely have greater willingness to
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Furthermore permanent cardiac pacemaker implantation may
2019-06-18

Furthermore, permanent cardiac pacemaker implantation may be required when severe bradyarrhythmia recurs for a long period. Sympathetic preganglionic neurons innervating the order JNJ-10198409 may be damaged beyond recovery in such cases [2]. Since placement of new leads immediately after infected l
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